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ERCSB NEWS
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이상혁 교수, Cancer Cell에 위암 유전단백체 논문 게재 (1/15)
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| 2019-01-15 14:46 written by admin (2024-04-27 07:02 Modify) | |
이화시스템생물학연구소의 이상혁 교수와 김상옥 박사과정 학생이 공동교신저자 및 공동제1저자로 참여한 국내 공동 연구진이 40대 전후로 발병하는 ‘조기 발병 위암(Early-onset gastric cancer)’의 유전적 원인을 밝혔다.
과학기술정보통신부 포스트 게놈 다부처 유전체 사업의 일환으로 진행된 연구진은 5년간 80명의 조기발병 위암 환자로부터 암조직과 주변 정상조직을 얻어 차세대염기서열분석법(NGS)과 단백체 연구방법을 통하여 원인성 유전자 변이를 밝히고 환자군의 상세 분류 방법을 개발하였다.
해당 연구는 미만성 위암의 발병 분자 기전을 규명하여 위암 정밀의료의 근거를 제공한다는 의의가 있으며, 본교의 연구팀은 유전체 데이터 분석 역할을 담당하였다.
본 논문은 국제적 저명학술지 Cell의 자매지인 Cancer Cell (Impact Factor = 22.844)에 2019년 1월 15일자 온라인 게재되었다. |
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