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김완규 교수팀, 한국생물정보시스템생물학회와 한국유전체학회 최우수포스터상 수상
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| 2016-02-17 18:50 written by admin (2024-12-22 10:46 Modify) | |
Untitled document
권예지 (좌, 대학원생), 이해승 (우, 포스트닥)
이화여자대학교 생명과학과 김완규 교수 연구실의 박사과정 권예지와 포스트닥 이해승 연구원이 한국생물정보시스템생물학회(KSBSB)와 한국유전체 동계학회에서 각각 최우수 포스터상을 수상하였다.
박사과정 권예지는 지난 2015년 10월 21일~23일 개최된 2015 한국생물정보시스템생물학회 추계학술대회 포스터발표 최우수상을 수상하였다. 연구 제목은 'Data-driven Drug Discovery for a Thousand Targets'로서, 대량의 생물학적 검정 (bioassay) 데이터를 활용하여 특정 단백질을 타겟하는 새로운 화합물(약물 후보 물질)을 효율적으로 가상 탐색하는 새로운 방법 (BEAR: Bioactive compound Enrichment by Assay Repositioning)을 제안하였다.
박사후 과정 이해승 연구원은 2016년 2월1일부터 3일사이 한국유전체학회가 주최한 제12회 한국유전체학회 동계 심포지엄 2016 에서으로 최우수 포스터상을 수상했다. 발표한 연구 제목은 'Drug repositioning for cancer therapy based on large-scale drug-induced transcriptional signature'으로서, 약물 처리에 의한 대규모 전사체 데이터를 기반으로 뇌종양에 효과적인 후보 약물을 예측하는 in silico 신약 재창출(drug repositioning) 방법을 개발하고, 다수의 환자유래의 뇌종양세포주에서 그 효과를 검증하고, 전사체 수준에서 검증된 약물의 작용 기전을 해석한 것이다.
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