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이상혁 교수, lncRNAtor 논문 Bioinformatics 지에 온라인 게재 (5/9)
2014-05-13 16:29 written by admin (2024-12-22 11:24 Modify)
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이화시스템생물학연구소 이상혁 교수는 단백질을 만들지 않고 세포내에서 다양한 조절기능을 담당하는 lncRNA (long noncoding RNA)에 대한 총체적인 정보를 제공하는 lncRNAtor 데이터베이스를 개발하여 생명정보 분야의 최고 학술지인 Bioinformatics지에 논문을 게재하였다 (Impact Factor 5.323, SCI Mathematical & Computational Biology 분야 47개 학술지 중 2위).

 

lncRNAtor 데이터베이스는  공개 정보의 데이터 마이닝을 통하여 lncRNA에 대한 서열 분석, 발현 패턴, 단백질 결합 등의 정보를 취합하였고, lncRNA의 기능을 온라인 상에서 분석하고 유추할 수 있도록 다양한 분석 방법을 지원한다. 또한 여러 종에서 서열과 발현 패턴이 동시에 보존되는 lncRNA를 발굴하여 세포내에서 기능을 갖는 lncRNA 후보를 제시하였다.

 

해당 논문 링크: http://bioinformatics.oxfordjournals.org/content/early/2014/05/09/bioinformatics.btu325.abstract 

웹사이트 링크: http://lncrnator.ewha.ac.kr/ 
첨부

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